Statement of Need/Program Overview

Early and accurate diagnosis of Alzheimer’s disease (AD) allows for patients to receive care earlier in the disease, which is especially important in the current landscape of emerging disease-modifying therapies (DMTs) for AD. The incorporation of biomarkers can further augment the diagnostic process to aid in earlier diagnosis of AD and prompt therapeutic intervention. In this educational podcast, join faculty Richard S. Isaacson, MD, and Charles P. Vega Jr, MD, as they provide an expert review on the association between biomarkers and clinical symptoms of AD, the use of biomarkers for early detection of AD, and the use of available and emerging DMTs for AD.  

Target Audience
This activity has been designed to meet the educational needs of dementia specialists, neurologists, primary care physicians, and advanced practice providers in neurology and primary care.

Learning Objectives
Upon completion of this activity, learners should be better able to:

• OUTLINE the temporal association between AD neuropathological markers and clinical symptoms for early recognition and staging of AD
• IMPLEMENT validated fluid and imaging biomarkers for the early detection of AD neuropathology 
• ASSESS the potential of available and emerging DMTs for AD according to their clinical efficacy, safety, and mechanism of action

Faculty
Richard S. Isaacson, MD (Chair) 
Adjunct Associate Professor, Department of Neurology
Weill Cornell 
New York, NY
Director, Center for Brain Health
Director, Alzheimer’s Prevention Clinic
Schmidt College of Medicine
Florida Atlantic University
Boca Raton, FL

Charles P. Vega Jr, MD
Health Sciences Clinical Professor of Family Medicine
Assistant Dean for Culture and Community Education
UC Irvine School of Medicine
Executive Director
UC Irvine Program in Medical Education for the Latino Community
Irvine, CA

Providership & Support

This educational activity is jointly provided by Albert Einstein College of Medicine-Montefiore Medical Center and Spire Learning.

This activity is supported by an educational grant from Lilly.

Disclosures of Conflicts of Interest

The “Policy on Identification, Mitigation and Disclosure of Relevant Financial Relationships” of Albert Einstein College of Medicine-Montefiore Medical Center requires that faculty participating in any CME/CE activity disclose to the audience any relevant relationships with an ineligible company or companies.* Any presenter whose disclosed relationships prove to create a conflict of interest, with regard to his or her contribution to the activity, will not be permitted to present. 

Albert Einstein College of Medicine-Montefiore Medical Center also requires that faculty participating in any CME/CE activity disclose to the audience when discussing any unlabeled or investigational use of any commercial product or device, not yet approved in the United States.

All relevant financial relationships and potential conflicts of interest have been mitigated.

*The ACCME defines an ineligible company as those whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

Faculty

Richard S. Isaacson, MD (Chair) 
Adjunct Associate Professor, Department of Neurology
Weill Cornell 
New York, NY
Director, Center for Brain Health
Director, Alzheimer’s Prevention Clinic
Schmidt College of Medicine
Florida Atlantic University
Boca Raton, FL

Disclosure

Dr. Isaacson has no relevant financial relationship with any ACCME-defined ineligible company in the past 24 months.

Charles P. Vega Jr, MD
Health Sciences Clinical Professor of Family Medicine
Assistant Dean for Culture and Community Education
UC Irvine School of Medicine
Executive Director
UC Irvine Program in Medical Education for the Latino Community
Irvine, CA

 
Disclosure

Dr. Vega has no relevant financial relationship with any ACCME-defined ineligible company in the past 24 months.

Educational Planning Committee
Spire Learning Disclosures
Ashton Webb, PharmD, BCACP (Clinical Director), Mairead Early (Program Manager), and Allison Goldberg, MPA (Senior Director, Grants and Education), have no relevant financial relationship with an ACCME-defined ineligible company in the past 24 months.

Reviewers

David M. Kaufman, MD (Peer Reviewer)

Professor, The Saul R. Korey Department of Neurology
Professor, Department of Psychiatry and Behavioral Sciences
Albert Einstein College of Medicine
Montefiore Medical Center
Bronx, NY

Disclosure:
Dr Kaufman has no relevant financial relationship with an ACCME-defined ineligible company in the past 24 months.

Victor B. Hatcher, PhD (CME Reviewer)
Professor of Biochemistry and Medicine
Associate Dean, Continuing Professional Development
Albert Einstein College of Medicine
Montefiore Medical Center
Bronx, NY

Disclosure:
Dr Hatcher has no relevant financial relationship with an ACCME-defined ineligible company in the past 24 months.

Disclosure of Unlabeled or Investigational Use
This educational activity does not contain discussion of unlabeled and/or investigational uses of agents that are not indicated by the FDA. Albert Einstein College of Medicine-Montefiore Medical Center and Spire Learning do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Disclaimer
Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed in this activity should not be used by clinicians without evaluation of patient conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

Privacy Policy
Albert Einstein College of Medicine-Montefiore Medical Center, Center for Continuing Professional Development (Einstein-Montefiore) protects the privacy of personal and other information regarding participants and educational collaborators. Einstein-Montefiore will not release personally identifiable information to a third party without the individual’s consent, except such information as is required for reporting to the ACCME. Einstein-Montefiore maintains physical, electronic, and procedural safeguards that comply with federal regulations to protect against the loss, misuse, or alteration of information collected from you. Additional information regarding Albert Einstein College of Medicine-Montefiore Medical Center’s Privacy Policy can be viewed at https://www.mecme.org/PrivacyStatement.aspx

Spire Learning, LLC is committed to protecting the privacy of personal information from our participants and educational collaborators. Spire maintains physical, electronic, and procedural safeguards that comply with federal regulations to protect against the loss, misuse, or alteration of personal information.
 
Collection and use of your personal information
The submission of certain personally identifiable information is necessary to award and track the credits participants may earn after completing an activity. Required items include first name, last name, degree, address, phone number and email address. These items are necessary. Participants are also required to complete an evaluation of each activity. All evaluative information submitted is collected and retained, and used by Spire Learning, LLC to continuously improve the learning experience.
 
Spire Learning, LLC will not transfer, sell, or share personal information with outside parties or otherwise disclose personal information unless required to in a legal process. Spire will retain your personal data only for the period necessary to accomplish the stated purposes and to comply with applicable laws.

Copyright Information
Copyright © 2022 by Albert Einstein College of Medicine-Montefiore Medical Center and Spire Learning, LLC. All rights reserved including translation into other languages. No part of this publication or activity may be reproduced or transmitted in any form, by any means, without prior written permission of Albert Einstein College of Medicine-Montefiore Medical Center and Spire Learning, LLC.

Course Viewing Requirements
Supported Browsers:
Internet Explorer 8.0+ for Windows 2003, Vista, XP, Windows 7, Windows 8.1 and above
Google Chrome 28.0+ for Windows, Mac OS, or Linux
Mozilla Firefox 23.0+ for Windows, Mac OS, or Linux
Safari 6.0+ for Mac OSX 10.7 and above

Supported Phones & Tablets:
Android 4.0.3 and above
iPhone/iPad with iOS 6.1 or above